Vitamin B2 (Riboflavin) — Pharma Raw Material Supplier, Hyderabad
Product Overview
Vitamin B2 (Riboflavin) is a water-soluble B-vitamin essential for energy production, cellular growth, and antioxidant function. It gives formulations a characteristic yellow colour and is a key component of B-complex pharmaceutical tablets, multivitamins, and energy metabolism supplements.
Specifications
| CAS Number | 83-88-5 |
| Molecular Formula | C₁₇H₂₀N₄O₆ |
| Molecular Weight | 376.36 g/mol |
| Appearance | Yellow to orange-yellow crystalline powder |
| Assay | 98.0–101.0% |
| Specific Rotation | -112° to -122° |
| Grades | IP / BP / EP / USP |
| Packaging | 25 kg HDPE bags |
Applications
- B-complex vitamin pharmaceutical tablets
- Multivitamin and mineral supplements
- Energy metabolism nutraceutical blends
- Migraine prevention supplements
- Sports nutrition formulations
- Yellow food colourant (E101)
Why Source from Surravi Phharma?
- Ready stock maintained in our centralised AC warehouse, Hyderabad
- IP / BP / EP / USP grades available
- Complete documentation: COA, MSDS, Regulatory certifications
- Flexible quantities — lab scale to bulk commercial
- Prompt delivery with pan India logistics support
Frequently Asked Questions
Where can I buy Riboflavin (Vitamin B2) pharma grade in Hyderabad?
Surravi Phharma supplies Riboflavin (Vitamin B2) in IP, BP, EP, and USP grades in Hyderabad with ready stock. Used in B-complex tablets, multivitamins, energy supplements, and as a yellow food colourant (E101). Available in 25 kg HDPE bags. Call +91 8008002576 for pricing and COA.
Why does Riboflavin give urine a bright yellow colour after supplementation?
Riboflavin is rapidly absorbed from the gut and excess amounts that exceed body saturation are excreted unchanged in urine, giving it a characteristic intense fluorescent yellow-green colour. This is completely harmless and is in fact used as a compliance marker in clinical trials — bright yellow urine confirms that the patient is taking their supplement. Patients should be counselled about this expected side effect when Riboflavin-containing formulations are dispensed.
Is Riboflavin photostable in pharmaceutical formulations?
Riboflavin is highly photosensitive — it degrades rapidly upon exposure to UV and visible light (particularly blue light, 450 nm). Pharmaceutical formulations containing Riboflavin must be protected from light through amber glass or opaque packaging, light-resistant coatings, and light-protective outer cartons. In liquid multivitamins, Riboflavin is one of the most challenging vitamins to stabilise. Riboflavin-5'-phosphate (FMN) is the more soluble coenzyme form used in some liquid formulations with improved stability.
What is the evidence for Riboflavin in migraine prophylaxis?
High-dose Riboflavin (400 mg/day) has Level A evidence from randomised controlled trials for migraine prevention in adults. The proposed mechanism is improved mitochondrial energy metabolism in neurons — Riboflavin is a cofactor for FAD and FMN, essential for the mitochondrial respiratory chain. Several neurology guidelines recommend Riboflavin 400 mg/day as a first-line preventive nutraceutical option for migraine. This application has driven significant demand for high-dose Riboflavin pharmaceutical raw material.