Vitamin C (Ascorbic Acid) — Pharma Grade Supplier, Hyderabad
Product Overview
Vitamin C (Ascorbic Acid) is a water-soluble vitamin and powerful antioxidant essential for collagen synthesis, immune function, and iron absorption. It is one of the highest-volume vitamin raw materials used in pharmaceutical tablets, effervescent formulations, nutraceutical immunity supplements, and fortified food products. Available in IP, BP, EP, and USP grades.
Specifications
| CAS Number | 50-81-7 |
| Molecular Formula | C₆H₈O₆ |
| Molecular Weight | 176.12 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Assay | 99.0–100.5% |
| Specific Rotation | +20.5° to +21.5° |
| Loss on Drying | NMT 0.4% |
| Grades | IP / BP / EP / USP |
| Packaging | 25 kg HDPE bags |
Applications
- Immunity supplement tablets and capsules
- Effervescent vitamin C tablet formulations
- Antioxidant nutraceutical supplement blends
- Collagen synthesis and skin health supplements
- Iron absorption enhancement formulations
- Food and beverage Vitamin C fortification
Why Source from Surravi Phharma?
- Ready stock maintained in our centralised AC warehouse, Hyderabad
- IP / BP / EP / USP grades available
- Complete documentation: COA, MSDS, Regulatory certifications
- Flexible quantities — lab scale to bulk commercial
- Prompt delivery with pan India logistics support
Frequently Asked Questions
Where can I buy Ascorbic Acid (Vitamin C) IP/USP pharma grade in Hyderabad?
Surravi Phharma supplies Ascorbic Acid (Vitamin C) in IP, BP, EP, and USP grades in Hyderabad. One of the highest-volume vitamin raw materials globally. Used in effervescent tablets, immunity supplements, antioxidant formulations, and food fortification. Ready stock in 25 kg HDPE bags. Call +91 8008002576 for pricing.
What is the difference between L-Ascorbic Acid and Sodium Ascorbate in formulations?
L-Ascorbic Acid is the pure acid form with a sour taste and pH of approximately 2.5 in solution. Sodium Ascorbate is the buffered, sodium salt form — pH neutral, non-acidic, and less irritating to the gastric mucosa, making it suitable for individuals with acid sensitivity. Sodium Ascorbate provides approximately 889 mg Vitamin C per gram (vs 1000 mg/g for pure Ascorbic Acid). Calcium Ascorbate is another buffered form preferred in formulations requiring mineral fortification. We supply L-Ascorbic Acid as standard; other forms available on request.
Why is Vitamin C particularly prone to degradation and how is it stabilised in formulations?
Ascorbic Acid is one of the most oxidation-sensitive vitamins. Key degradation factors: oxygen exposure, metal ion catalysis (Fe²⁺, Cu²⁺), high temperature, high moisture, and alkaline pH. Stabilisation strategies include: packaging in nitrogen-purged, moisture-barrier containers; use of antioxidant synergists (EDTA to chelate metal ions); coating with Ethylcellulose or HPMC film to reduce moisture uptake; formulating at pH 4–6; and using Ascorbyl Palmitate (fat-soluble form) for oil-based formulations. Effervescent Vitamin C formulations are particularly stable as the dry anhydrous environment minimises oxidation.
What is the megadose Vitamin C debate and what does current evidence support?
Linus Pauling famously advocated doses of 1,000–10,000 mg/day for immunity and cancer prevention. Current evidence shows: the immune benefits are clinically relevant primarily in physically stressed populations (athletes, people in cold environments) at 200–1000 mg/day; megadoses above 2,000 mg/day offer no additional benefit over 200–400 mg and increase risk of kidney oxalate stones and GI distress; plasma Vitamin C saturates at approximately 200 mg/day oral intake. The recommended therapeutic range for immunity support in most evidence-based guidelines is 200–1,000 mg/day.
Can Vitamin C enhance iron absorption and how is this used in pharmaceutical formulations?
Yes. Vitamin C (Ascorbic Acid) dramatically enhances non-haem iron absorption by reducing insoluble Fe³⁺ to soluble Fe²⁺ and chelating iron in a form that remains soluble at intestinal pH. Studies show that 100–200 mg of Vitamin C taken simultaneously with iron supplements can increase iron absorption by 2–4×. This is the basis for combination iron + Vitamin C pharmaceutical products, which are standard in iron-deficiency anaemia treatment, particularly in India where dietary iron deficiency is widespread.