Vitamin E (Tocopherol / Tocopheryl Acetate) — Pharma Grade Supplier, Hyderabad
Product Overview
Vitamin E encompasses a family of fat-soluble antioxidants, with d-alpha-Tocopherol (natural) and dl-alpha-Tocopheryl Acetate (synthetic) being the most widely used pharmaceutical forms. Vitamin E is essential for antioxidant protection, immune function, skin health, and cardiovascular wellness. Tocopheryl Acetate is the more stable esterified form preferred in solid dosage form tablets and capsules.
Specifications
| CAS Number | 59-02-9 (Tocopherol); 58-95-7 (Tocopheryl Acetate) |
| Appearance | Tocopherol: yellow viscous oil; Tocopheryl Acetate: white powder (dry form) |
| Potency (Tocopherol) | 1000–1360 IU/g |
| Potency (Tocopheryl Acetate) | 910–1000 IU/g |
| Available Forms | d-alpha-Tocopherol, dl-alpha-Tocopheryl Acetate |
| Grades | IP / BP / EP / USP |
| Packaging | 1 kg / 5 kg / 25 kg |
Applications
- Antioxidant nutraceutical supplement formulations
- Skin health and anti-aging topical preparations
- Cardiovascular health supplement products
- Multivitamin tablet and softgel capsule formulations
- Natural preservative antioxidant in oils and fats
- Male fertility and reproductive health supplements
Why Source from Surravi Phharma?
- Ready stock maintained in our centralised AC warehouse, Hyderabad
- IP / BP / EP / USP grades available
- Complete documentation: COA, MSDS, Regulatory certifications
- Flexible quantities — lab scale to bulk commercial
- Prompt delivery with pan India logistics support
Frequently Asked Questions
Where can I buy Vitamin E (Tocopherol / Tocopheryl Acetate) pharma grade in Hyderabad?
Surravi Phharma supplies Vitamin E as d-alpha-Tocopherol (natural) and dl-alpha-Tocopheryl Acetate (synthetic) in IP, BP, EP, and USP grades in Hyderabad. Available in oil and dry powder forms. Ready stock in 1 kg, 5 kg, and 25 kg packaging. Call +91 8008002576 for pricing.
What is the difference between natural Vitamin E (d-alpha-Tocopherol) and synthetic (dl-alpha-Tocopheryl Acetate)?
Natural Vitamin E (d-alpha-Tocopherol from vegetable oils) contains only the RRR-alpha-tocopherol stereoisomer — the form preferentially retained by the body. Synthetic Vitamin E (dl-alpha-Tocopheryl Acetate) is a racemic mixture of 8 stereoisomers, of which only the RRR form is biologically active. Natural Vitamin E has approximately 1.36× greater biological activity per IU compared to synthetic. Products using natural Vitamin E can claim a 'natural Vitamin E' label, which commands a premium in nutraceutical markets. For formulations where the natural claim matters, specify d-alpha-Tocopherol.
Why is Tocopheryl Acetate preferred over Tocopherol in solid tablet formulations?
dl-alpha-Tocopheryl Acetate has the acetate ester protecting the active hydroxyl group, giving it significantly greater oxidative stability compared to free Tocopherol. It is available as a dry powder (adsorbed on silica or starch), making it easy to incorporate into tablet granulations and capsule fills. Free Tocopherol is an oil that must be encapsulated in softgels or microencapsulated for solid dose use. Tocopheryl Acetate is hydrolysed back to active Tocopherol in the intestinal wall before absorption — bioavailability is equivalent to free Tocopherol.
What is the role of Vitamin E as a natural antioxidant preservative in pharmaceutical oils?
Mixed tocopherols (a natural extract rich in alpha, beta, gamma, and delta tocopherols) are widely used as natural antioxidant preservatives in pharmaceutical and food-grade oils — including MCT oil, fish oil, soya oil, and other lipid excipients — at concentrations of 0.01–0.1% w/w. They prevent lipid peroxidation and rancidity by scavenging free radicals in the oil phase. This is an important application in softgel formulations containing omega-3 oils, Vitamin A, D, and E softgels, and any lipid-based drug delivery system.
What are the cardiovascular and male health applications of Vitamin E in nutraceuticals?
Vitamin E has established roles in male reproductive health — it protects sperm membranes from oxidative damage and is commonly combined with Selenium, Zinc, and CoQ10 in male fertility supplement formulations. In cardiovascular nutraceuticals, Vitamin E reduces LDL oxidation (a key step in atherosclerosis) and has anti-platelet properties. The HOPE and GISSI trials showed mixed cardiovascular outcomes with Vitamin E supplementation, suggesting that the combination of antioxidants (Vitamin C + E + Selenium) rather than isolated Vitamin E is more clinically relevant for cardiovascular protection.