D-Panthenol (Dexpanthenol) — Pharma Grade Supplier, Hyderabad
Product Overview
D-Panthenol (Dexpanthenol) is the alcohol analogue of pantothenic acid (Vitamin B5), readily converted to Vitamin B5 in the body. It is widely used in pharmaceutical topical preparations, hair care products, and nutraceuticals for its moisturising, wound-healing, and anti-inflammatory properties.
Specifications
| CAS Number | 81-13-0 |
| Molecular Formula | C₉H₁₉NO₄ |
| Molecular Weight | 205.25 g/mol |
| Appearance | Viscous, clear to pale yellow liquid |
| Assay | NLT 98.0% |
| Specific Rotation | +27.5° to +30.5° |
| Grades | IP / BP / EP / USP |
| Packaging | 25 kg HDPE drums |
Applications
- Topical skin and wound healing preparations
- Hair care formulations (shampoos, conditioners)
- Vitamin B5 supplement in nutraceuticals
- Ophthalmic drops and eye care products
- Nasal spray formulations
- Moisturising creams and lotions
Why Source from Surravi Phharma?
- Ready stock maintained in our centralised AC warehouse, Hyderabad
- IP / BP / EP / USP grades available
- Complete documentation: COA, MSDS, Regulatory certifications
- Flexible quantities — lab scale to bulk commercial
- Prompt delivery with pan India logistics support
Frequently Asked Questions
Where can I buy D-Panthenol (Dexpanthenol) pharma grade in Hyderabad?
Surravi Phharma supplies D-Panthenol (Dexpanthenol) in IP, BP, EP, and USP grades in Hyderabad. Used in topical wound healing preparations, hair care products, nasal sprays, and Vitamin B5 nutraceuticals. Ready stock in HDPE drums. Call +91 8008002576 for pricing and documentation.
What is the difference between D-Panthenol and Pantothenic Acid (Vitamin B5)?
Pantothenic Acid is the active vitamin form (Vitamin B5), but it is unstable in topical formulations and poorly absorbed through the skin. D-Panthenol is the alcohol precursor that converts to Pantothenic Acid after absorption — both through skin (topical) and via gut metabolism (oral). D-Panthenol is preferred in topical formulations because it penetrates the skin far more effectively than Pantothenic Acid and is converted to the active vitamin in the deeper layers.
What concentration of D-Panthenol is used in pharma and cosmetic preparations?
In topical wound healing and skin care preparations, D-Panthenol is used at 2–5% w/w. In hair care formulations (shampoos, conditioners), 0.1–1% is typical. In ophthalmic drops, 2–5% provides corneal lubrication and healing. In nasal sprays, 0.1–0.5% helps maintain mucosal moisture. For oral nutraceutical Vitamin B5 supplementation, D-Panthenol is typically dosed at 5–10 mg per serving.
Is D-Panthenol compatible with the other ingredients in cosmetic formulations?
D-Panthenol is water-soluble, odourless, and highly compatible with most cosmetic and pharmaceutical raw materials including surfactants, emollients, preservatives, and other active ingredients. It is stable at pH 4–7, which covers most topical formulation ranges. It should be added to formulations at the cool-down phase (below 40°C) to preserve activity, as prolonged heating above 70°C can cause partial degradation.
What clinical evidence supports D-Panthenol for wound healing?
D-Panthenol stimulates epithelialisation (skin cell proliferation and migration) and promotes granulation tissue formation in wound healing. Clinical studies show it accelerates healing of superficial wounds, burns, abrasions, and post-procedure skin recovery. It also reduces wound-related inflammation and maintains skin barrier function. It is a key active ingredient in numerous European pharmaceutical wound healing formulations and is approved as a pharmaceutical active in many markets.