L-Tryptophan — Pharma Grade Amino Acid Supplier, Hyderabad
Product Overview
L-Tryptophan is an essential amino acid and the dietary precursor to serotonin and melatonin. It is widely used in nutraceutical sleep quality, mood support, and stress management supplements. As the sole dietary precursor to 5-HTP, serotonin, and melatonin, it is a key ingredient in natural sleep and mental wellness formulations.
Specifications
| CAS Number | 73-22-3 |
| Molecular Formula | C₁₁H₁₂N₂O₂ |
| Molecular Weight | 204.23 g/mol |
| Appearance | White to slightly yellowish powder |
| Assay | 98.5–101.5% |
| Specific Rotation | -31.5° to -33.5° |
| Loss on Drying | NMT 0.3% |
| Grades | IP / BP / EP / USP |
| Packaging | 25 kg HDPE bags |
Applications
- Sleep quality and insomnia support supplements
- Mood and anti-anxiety nutraceutical formulations
- Serotonin precursor supplement products
- Stress and depression management nutraceuticals
- Parenteral nutrition amino acid solutions
- Appetite regulation and satiety supplement blends
Why Source from Surravi Phharma?
- Ready stock maintained in our centralised AC warehouse, Hyderabad
- IP / BP / EP / USP grades available
- Complete documentation: COA, MSDS, Regulatory certifications
- Flexible quantities — lab scale to bulk commercial
- Prompt delivery with pan India logistics support
Frequently Asked Questions
Where can I buy L-Tryptophan pharma grade IP/USP in Hyderabad?
Surravi Phharma supplies L-Tryptophan in IP, BP, EP, and USP grades in Hyderabad with ready stock. Used in sleep quality, mood support, and serotonin precursor supplement formulations. Available in 25 kg HDPE bags. Call +91 8008002576 for pricing and documentation.
How does L-Tryptophan increase serotonin and melatonin levels in the body?
L-Tryptophan is the sole dietary precursor to serotonin (5-hydroxytryptamine). The pathway is: Tryptophan → 5-HTP (via tryptophan hydroxylase) → Serotonin (via aromatic amino acid decarboxylase). In the pineal gland, Serotonin is further converted to Melatonin (the sleep hormone). This makes Tryptophan a foundational nutrient for both mood regulation (via serotonin) and circadian sleep rhythms (via melatonin). This dual pathway explains the use of L-Tryptophan in both sleep quality and anti-anxiety supplement formulations.
What is the difference between L-Tryptophan and 5-HTP supplements?
5-HTP (5-hydroxytryptophan) is the direct metabolic intermediate between Tryptophan and Serotonin. 5-HTP crosses the blood-brain barrier more efficiently than Tryptophan and requires one fewer enzymatic step to reach serotonin. At equivalent doses, 5-HTP produces greater serotonergic effects than Tryptophan. However, Tryptophan is a physiological amino acid with additional roles beyond serotonin synthesis (it's also used for protein synthesis and niacin production), making it the safer long-term supplement option. 5-HTP is used for more targeted, rapid serotonergic effect. Many formulations combine both.
What dose of L-Tryptophan is effective for sleep improvement?
Studies show sleep improvement with L-Tryptophan at 1–2 g taken 45–60 minutes before bedtime. The largest effect is seen in reducing the time to fall asleep (sleep latency) and improving early sleep quality in individuals with mild insomnia. At lower doses (0.25–1 g), Tryptophan can improve mood and reduce anxiety without significant sedation. For context, approximately 60 mg of Tryptophan is needed to produce 1 mg of 5-HTP, and approximately 10 mg 5-HTP produces 1 mg serotonin — explaining the relatively high dose requirements for Tryptophan-based sleep supplements.